Understanding the causes and risk factors of neuroendocrine tumors (NETs) helps individuals take preventive measures and seek early screening. Key contributors include:
- Genetic Syndromes: Conditions like MEN types 1 and 2, von Hippel-Lindau syndrome, or neurofibromatosis type 1 increase risk significantly.
- Family History: A family history of NETs or related cancers elevates susceptibility.
- Age & Gender: More common in adults over 50; risk may vary slightly by gender depending on tumor location.
- Chronic Conditions: Diseases such as chronic pancreatitis or inflammatory bowel disease may contribute to risk.
- Environmental Exposures: Limited evidence links certain toxins or radiation to increased risk.
- Lifestyle Factors: Smoking, excessive alcohol, or a diet high in processed foods may indirectly affect risk.
- Hormonal Imbalances: Abnormal hormone levels or endocrine disorders may trigger abnormal cell growth.