Understanding the causes and risk factors of soft-tissue sarcomas helps individuals take preventive measures and seek early screening. Key contributors include:
- Genetic Conditions: Inherited syndromes like Li-Fraumeni, neurofibromatosis, or Gardner syndrome.
- Radiation Exposure: Prior radiation therapy for other cancers.
- Chemical Exposure: Long-term contact with vinyl chloride, dioxins, or herbicides.
- Chronic Lymphedema: Persistent swelling due to lymph node issues.
- Family History: Sarcomas or related cancers in close relatives.
- Viral Infections: Certain viruses, like HHV-8, linked to specific sarcomas.
- Age & Gender: Some types are more common in adults; certain subtypes show slight gender predilection.